Endocrine Abstracts

Background: Polycystic ovary syndrome (PCOS) is clinically associated with increased risk of CVD. Thrombin generation (TG) is a measure of the thrombotic potential. This can be expressed as endogenous thrombin potential (ETP) representing the total amount of generated active thrombin over the time (nmol/l×min). ETP is considered the most predictive parameter of thrombosis and is associated to both venous and arterial thrombotic disease. Setting: PCOS women prospectively r...

Background: Polycystic ovary syndrome (PCOS) is according to the Rotterdam criteria defined as minimum two of: oligomenoré, hyperandrogenism and polycystic ovary. These criteria do not take into account PCOS’ association with the metabolic syndrome (MES) and ischaemic heart disease (IHD). Recently we grouped PCOS- patients into four phenotypes depending on normal/high BMI and insulin resistance (IR). We demonstrated that PCOS-patients with high BMI and increased IR h...